Acetyl-L-Carnitine

Scientific Effect

Acetyl-L-Carnitine is naturally produced by the body and is involved in fat metabolism. Supplementation may contribute to improvements in many facets of health.



Clinical Study

The supplementation of acetyl-L-carnitine decreases fatigue and increases quality of life in patients with hepatitis C treated with pegylated interferon-α 2b plus ribavirin.

Results

"ALC supplementation reduced both mental and physical fatigue, improved health-related quality of life..."

Study Citation

Malaguarnera, M., Vacante, M., Bertino, G., Neri, S., Malaguarnera, M., Gargante, M. P., ... & Pennisi, G. (2011). The supplementation of acetyl-L-carnitine decreases fatigue and increases quality of life in patients with hepatitis C treated with pegylated interferon-α 2b plus ribavirin. Journal of Interferon & Cytokine Research, 31(9), 653-659.

Link


Clinical Study

The results of this study suggest that ALC can reduce craving and the time to first drink.

Results

Acetyl-L-carnitine for alcohol craving and relapse prevention in anhedonic alcoholics: a randomized, double-blind, placebo-controlled pilot trial.

Study Citation

Martinotti, G., Reina, D., Di Nicola, M., Andreoli, S., Tedeschi, D., Ortolani, I., ... & Janiri, L. (2010). Acetyl-L-carnitine for alcohol craving and relapse prevention in anhedonic alcoholics: a randomized, double-blind, placebo-controlled pilot trial. Alcohol & Alcoholism, 45(5), 449-455.

Link


Clinical Study

Acetyl-L-carnitine safely ameliorated arterial hypertension, insulin resistance, impaired glucose tolerance, and hypoadiponectinemia in subjects at increased cardiovascular risk.

Results

Ameliorating hypertension and insulin resistance in subjects at increased cardiovascular risk: effects of acetyl-L-carnitine therapy.

Study Citation

Ruggenenti, P., Cattaneo, D., Loriga, G., Ledda, F., Motterlini, N., Gherardi, G., ... & Remuzzi, G. (2009). Ameliorating hypertension and insulin resistance in subjects at increased cardiovascular risk: effects of acetyl-L-carnitine therapy. Hypertension, 54(3), 567-574.

Link