Scientific Effect
MSM is an organic sulfur compound that is found in some plants. It may be effective in improving the symptoms of arthitis and seasonal allergies.
Clinical Study
Efficacy of methylsulfonylmethane (MSM) in osteoarthritis pain of the knee: a pilot clinical trial.
Results
"MSM (3g twice a day) improved symptoms of pain and physical function during the short intervention without major adverse events."
Study Citation
Kim, L. S., Axelrod, L. J., Howard, P., Buratovich, N., & Waters, R. F. (2006). Efficacy of methylsulfonylmethane (MSM) in osteoarthritis pain of the knee: a pilot clinical trial. Osteoarthritis and Cartilage, 14(3), 286-294.
LinkClinical Study
Patients with osteoarthitis of the knee taking MSM for 12 weeks showed an improvement in pain and physical function.
Results
"Efficacy of methylsulfonylmethane supplementation on osteoarthritis of the knee: a randomized controlled study."
Study Citation
Debbi, E. M., Agar, G., Fichman, G., Ziv, Y. B., Kardosh, R., Halperin, N., ... & Debi, R. (2011). Efficacy of methylsulfonylmethane supplementation on osteoarthritis of the knee: a randomized controlled study. BMC complementary and alternative medicine, 11(1), 50.
LinkClinical Study
...MSM supplementation of 2,600 mg/day for 30 days may be efficacious in the reduction of symptoms associated with seasonal allergic rhinitis.
Results
"A multicentered, open-label trial on the safety and efficacy of methylsulfonylmethane in the treatment of seasonal allergic rhinitis."
Study Citation
Barrager, E., Veltmann Jr, J. R., Schauss, A. G., & Schiller, R. N. (2002). A multicentered, open-label trial on the safety and efficacy of methylsulfonylmethane in the treatment of seasonal allergic rhinitis. The Journal of Alternative & Complementary Medicine, 8(2), 167-173.
Link