Scientific Effect
PABA is an ubiquitous organic compound involved in folate synthesis. It may play a role in decreasing the incidence of lung and skin fibrosis.
Clinical Study
Conservative management options for peyronie’s disease.
Results
"Potassium paraaminobenzoate (PABA...) appears to have an anti-inflammatory and antifibrotic effect..."
Study Citation
Jack, G. S., Gonzalez-Cadavid, N., & Rajfer, J. (2005). Conservative management options for Peyronie’s disease. Current urology reports, 6(6), 454-460.
LinkClinical Study
...The average decrease for both vital capacity and CO diffusing capacity was found to be less for KPAB-treated patients.
Results
"Retrospective studies in scleroderma: pulmonary findings and effect of potassium p-aminobenzoate on vital capacity."
Study Citation
Zarafonetis, C. J., Dabich, L., Devol, E. B., Skovronski, J. J., Negri, D., & Yuan, W. (1989). Retrospective studies in scleroderma: pulmonary findings and effect of potassium p-aminobenzoate on vital capacity. Respiration, 56(1-2), 22-33.
LinkClinical Study
Other alternative symptomatic therapy including Para-aminobenzoic acid decreases the progression of skin fibrosis and improves survival.
Results
"Treatment of scleroderma with para-aminobenzoic acid: effect on disease morbidity."
Study Citation
Sawalha, K. Treatment of scleroderma with para-aminobenzoic acid: effect on disease morbidity. Arch Gen Intern Med. 2018; 2 (3): 19-22. DOI: 10.4066/2591-7951.1000052 Arch Gen Intern Med 2018 Volume 2 Issue, 3.
Link