Pyridoxal 5 Phosphate (P5P, Vitamin B6)




Scientific Effect

Vitamin B(6) supplementation improves pro-inflammatory responses in patients with rheumatoid arthritis.



Clinical Study

Vitamin B(6) supplementation improves pro-inflammatory responses in patients with rheumatoid arthritis.

Results

"A large dose of vitamin B(6) supplementation (100 mg/day) suppressed pro-inflammatory cytokines (that is, IL-6 and TNF-alpha) in patients with RA."

Study Citation

Huang, S. C., Wei, J. C., Wu, D. J., & Huang, Y. C. (2010). Vitamin B 6 supplementation improves pro-inflammatory responses in patients with rheumatoid arthritis. European journal of clinical nutrition, 64(9), 1007.

Link


Clinical Study

With the addition of vitamin B6 to their treatment, four patients had clinically significant (greater than 30%) improvement on the measures of involuntary movement...

Results

"Vitamin B6 in treatment of tardive dyskinesia: a preliminary case series study."

Study Citation

Lerner, V., Kaptsan, A., Miodownik, C., & Kotler, M. (1999). Vitamin B6 in treatment of tardive dyskinesia: a preliminary case series study. Clinical neuropharmacology, 22(4), 241-243.

Link


Clinical Study

At the completion of 3 days of therapy, only eight of 31 patients in the vitamin B6 group had any vomiting, compared with 15 of 28 patients in the placebo group.

Results

"Vitamin B6 is effective therapy for nausea and vomiting of pregnancy: a randomized, double-blind placebo-controlled study."

Study Citation

Sahakian, V., Rouse, D. W. I. G. H. T., Sipes, S. U. S. A. N., Rose, N. A. N. C. Y., & Niebyl, J. E. N. N. I. F. E. R. (1991). Vitamin B6 is effective therapy for nausea and vomiting of pregnancy: a randomized, double-blind placebo-controlled study. Obstetrics and gynecology, 78(1), 33-36.

Link